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Kerrisdale Capital Management is an investment management company that was founded by Sahm Adrangi who also serves as the Chief Investment Officer. The firm focuses on mostly event driven special situations and long term value investments. Kerrisdale Capital has a short position at a company they previously gave a negative report, Proteostasis Therapeutics. This is a clinical stage biopharmaceutical company that discovers and develops therapeutics to treat among other diseases, cystic fibrosis. One such novel therapeutic is their lead product, PTI-428.

In claims refuted by Sahm Adrangi’s Kerrisdale Capital, Proteostasis claims that PTI-428 works uniquely by increasing levels of messenger RNA and protein correspondence to the gene CFTR. They supposedly performed a clinical trial that showed the drug meaningfully improved lung function as compared to placebo. In response, Sahm Adrangi and Kerrisdale Capital argued that these results were not wholly true. This is because the patients who received PTI-428 did not necessarily react extremely good to it, but rather the patients on placebo reacted poorly. On the other hand, CFTR mRNA and protein are very scarce in even the airway epithelium, further proving the drug is not as effective as Proteostasis claim because it would not be easy to measure favored biomarkers.

Sahm Adrangi has been with Kerrisdale Capital Management since founding it in 2009. Kerrisdale Capital Management is based in New York and makes value-oriented investments in public securities. He had previously held various positions in other companies. Among them, he was an Investment Analyst at Longacre Fund Management, LLC, Analyst at Chanin Capital Partners and Analyst at Deutsche Bank. Sahm Adrangi is a graduate of Yale University, where he received a Bachelor of Arts in Economics in 2003. He is widely known for exposing fraudulent companies and action against these companies taken by the Securities and Exchange Commission. Under Sahm Adrangi, Kerrisdale has published reports on specific sectors it acquaints with like mining, telecommunications and biotechnology. He is also a known activist, speaker and has as well appeared in interviews at Bloomberg and CNBC.

Seattle Genetics has put its primary focus on the study, manipulation, and packaging into drugs of the human antibodies. The firm has been concentrating on this since it was founded in 1998. The power that is in the antibodies from the company lies in their ability to connect to something else. These antibodies are capable of destroying the cancer cells from the inside by delivering a toxic payload. This strategy could make Seattle Genetics become one of the big league companies. It could become big enough to be the firm that the biotech community of Seattle has been striving to anchor.

Seattle Genetics is already the biggest biotech company in Washington, with a market value of almost 10 billion dollars. The firm mostly invests in the research and marketing sectors. In 2017, they were able to add in 200 more workers. Clay Siegall, the CEO, president, chairman, and co-founder of the firm, claims that they are coming up with a global multiproduct. Clay Siegall has the ambition and desire to move past the typical drug development of most biotech firms. He hopes to come up with a great company instead of having to sell to a larger company, which is the trend of most biotech firms.

The company is now changing the trend of what they did in its early years of development when they sold part of their shared to Takeda Oncology. The partnership of Seattle Genetics with Takeda has helped it to learn about global markets. This has led to the recent opening of an office in Switzerland by Clay Siegall so that it can do its international marketing. Seattle Genetics has 11 drugs in their pipeline. However, Clay Siegall says that four of those are the ones with the higher potential for immediate sales. These drugs include; Adcetrics, 33A, 22ME, and LIV1.

Clay Siegall was a co-founder of Seattle Genetics in 1998. He is the Chief Executive Officer, President and member of the Board of Directors of the firm. This firm is coming up with new clinical and preclinical products candidates. Their primary target is in various cancer and autoimmune indications. Dr Siegall has guided the firm in its activities of raising capital. He oversaw Seattle Genetics in the first public offering in the year 2001. Clay has also helped the company to enter into various strategic collaborations. Some of these collaboration agreements are with Genentech, MedImmune, Bayer and Progenics, and MedImmune. These ADC collaborations have helped in generating over 65 million dollars since 2001.

Like so many businessmen and entrepreneurs before him, Clayton Hutson owns his operations, and he has a hand on the wheel as a result of years of service. His business is service oriented, and it caters to the needs of musicians along with the event planners who make artists look like geniuses. Hutson’s training is in theater design, and some of his past clients include names such as Guns and Roses, Pink and Kidd Rock.


He is not a man who shies away from any particular genre of music. But at the same time, he admits to gravitating toward Rock and Roll. One of his most memorable work experiences is the “Bleed Like Me” tour for Garbage. But, there are other projects such as the “Honda Civic Tour” for OneRepublic that really showcase his professional skill set and creative vision.


There really is no specific moment when he knew it was time to strike out on his own. And like many successful business owners who are also operators, his move to the top was one of necessity. To get the best reward for the effort he gives, running his own firm is the only way to go.


When he is in the process of designing a new concept or image for his business, Clayton makes sure to keep things based in reality. This means that whatever he comes up with has to fit through venue doors or his clients and their clients as well have no use for them. For this exact reason, he incorporates technology and precision in his creative process religiously. This sharp method of production is one of the key elements that allows him to stay relevant in his field.


Where art and entertainment is concerned, one unforgettably sloppy mistake can be costly. It can take years to rebuild a reputation, if ever. So, Hutson makes sure to produce quality concepts and work product, which requires long hours striving for perfection. This means that his work day usually starts at 7am, and it goes until every detail is resolved. And even though he calls the shots in the office, Hutson understands and appreciates all the hard work that his staff does as well. Learn more:


Todd Lubar has invested in many different ventures during his career from scrap metal to real estate. His is a hard worker, stands by his work ethics and has become a successful businessman. The combination of his skills and experience have placed him in a position where he is able to provide assistance for other businesses using is time tested methods. He has effectively streamlined the processes of TDL Global as the President of the company. His clients have excelled with his aid on numerous occasions. For more details visit Ideamensch.


Todd Lubar has had entrepreneurial tendencies for as long as he can remember. He is motivated and further inspired by his actions. He achieves pride from his accomplishments and enjoys inspiring the people around him. He believes there is a strong correlation between the environment and success. His accomplishments have not always come easily. He has had to find his own route to succeed. This has taught him the value and importance of loyalty and trust. Todd Lubar admits the biggest motivator in his life has been fear. The mortgage industry taught him he had to work to earn a paycheck and this kept him motivated to succeed.


Todd Lubar developed an interest in real estate while he was working in the mortgage industry. He started recognizing patterns and saw the profits the sellers achieved. This was when he acquired his first business in real estate. The profits enabled him to buy a second home and continued to accumulate. Todd is always making an effort to increase his teams productivity to ensure his business is operating at the highest possible capacity. He spends time every day motivating his team and solving problems. Check out Yelp to see more.


Todd Lubar is interested in businesses and industries capable of large revenue numbers. He believes it is no harder to operate a business generating billions than thousands. His current focus is on the insurance business due to the enormous potential for revenue. He feels call centers also have a lot of potential for revenue due to the volume of service, training staff and streamlined processes. He is confident in his actions, skills and goals. There is no doubt he has achieved success.



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